The autoimmune diseases

The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P's" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment. -- Publisher.

<P>A. General Considerations</p> <p>1. Autoimmune Disease: The Consequence of Disturbed Homeostasis</p><i> <p>Ian Mackay and Noel R. Rose</p></i> <p>2. Autoimmunity: A History of the Early Struggle for Recognition</p><i> <p>Arthur M. Silverstein</p></i> <p>3. General Features of Autoimmune Disease </p><i> <p>Anne Davidson and Betty Diamond</p></i> <p>4. Innate and AdaptiveSystems of Immunity</p><i> <p>Peter Delves</p></i> <p>B. Adaptive Immunity and Autoimmune Disease -- T & B Cells</p> <p>5. Immunological Tolerance-T Cells</p><i> <p>Jakub Abramson</p></i> <p>6. T Cells and their Subsets in Autoimmunity</p><i> <p>Vijay Kumar Kuchroo</p></i> <p>7. The Role of Invariant Natural Killer T Cells in Autoimmune Diseases</p><i> <p>Mitchell Kronenberg</p></i> <p>8. B Cell Development: How to Become One of the Chosen Ones</p><i> <p>Fritz Melchers</p></i> <p>9. B Cell Activation and B Cell Tolerance </p><i> <p>Claudia Mauri</p></i> <p>C. Cells and Molecules of the Immune System</p> <p>10. Role of Macrophages in Autoimmunity</p><i> <p>Luisa Martinez-Pomares</p></i> <p>11. Dendritic Cells in Autoimmune Disease</p><i> <p>Kristin Tarbell</p></i> <p>12. Natural Killer Cells</p><i> <p>Yenan Bryces…