The lung: development, aging and the environment

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment. * Discusses the mechanisms that regulate the initial events of lung morphogenesis * Provides a better understanding of the cellular and biochemical events involved in alveolarization * Development of the pulmonary immune system and how the exposure to allergens during development may lead to diseases such as asthma.

Lung morphogenesis, role of growth factors and transcription factors / Wellington V. Cardoso -- Development of airway epithelium / Charles G. Plopper, Michelle V. Fanucchi -- Development of the airway innervation / Malcolm P. Sparrow, Markus Weichselbaum, Jenny Tollet, Peter K. McFawn, John T. Fisher -- Development of alveoli / Stephen E. McGowan, Jeanne M. Snyder -- Development of the pulmonary basement membrane zone / Michael J. Evans, Philip L. Sannes -- Development of the pulmonary vasculature / Rosemary Jones, Lynne M. Reid -- Developmental physiology of the pulmonary circulation / Steven H. Abman -- Development of fluid transport pulmonary epithelia / Jonathan H. Widdicombe -- Physical, endocrine and growth factors in lung development / Stuart B. Hooper, Megan J. Wallace -- Development of the pulmonary surfactant system / Sandra Orgeig, Christopher B. Daniels, Lucy C. Sullivan -- Development of the pulmonary immune system / Lisa A. Miller.

Development of antioxidant and xenobiotic metabolizing enzyme systems / Michelle V. Fanucchi -- Compensatory lung growth : relationship to postnatal lung growth and adaptation in destructive lung disease / Connie C.W. Hsia, Robert L. John…