Title Statements
- Full title :Thyroid Hormone.
Summary
Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics.--
Read More ↓Publication Statements
- Publisher(s):InTech
- Place of Publication:S.l
- Language:eng
The Physical Object
- Description:1 online resource
Edition Identifiers
- ISBN:9535106783, 9789535106784, 9780128141175, 0128141174
- oclc:on1096661179
- LC Classification:QP572.T5
- Dewey Decimal:612.44
Table of Contents
Front Cover; Thyroid Hormone; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Local Regulation of Thyroid Hormone Signaling; 1. Introduction; 2. Bioavailability; 2.1. TH Transporters; 2.2. Deiodinases; 2.3. Intracellular Reservoir Proteins; 3. Bioactivity; 3.1. Thyroid Receptors; 3.2. Integrin I v A#x9F;3; 3.3. Thyroid Response Elements; 4. Conclusions; References; Further Reading; Chapter Two: Thyroid Hormone Transport and Transporters; 1. Introduction; 2. Thyroid hormone Transport; 3. Monocarboxylate Transporter 8; 3.1. The Syndrome of Inherited MCT8 Deficiency
3.2. Mutations in MCT8 Impair Thyroid Hormone Transport3.3. Concepts for Treatment of MCT8 Deficiency; 3.3.1. Raising Low T4; 3.3.2. Lowering Elevated T3; 3.3.3. Replacing Thyroid Hormone With an MCT8-Independent Agonist; 4. Mouse Models of Allan-Herndon-Dudley Syndrome; 5. Thyroid Hormone Transport and Physiology; 6. Further Clinical Implications for Thyroid Hormone Transporters; 6.1. Polymorphisms in Thyroid Hormone Transporters May Affect Thyroid Hormone Levels; 6.2. Inhibition of Thyroid Hormone Transport by Drugs; 6.3. Intestinal Uptake of T4 and Thyroid Hormone Transport
7. Conclusions and…
Subjects
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