Toxicogenomics in predictive carcinogenicity

by Thomas, Russell S. Waters, Michael D.

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Title Statements

Full title :Toxicogenomics in predictive carcinogenicity / editors: Russell S. Thomas, Michael D. Waters.

Edition Statements

Publication Date:2016.

Publication Statements

Publisher(s):Royal Society of Chemistry
Place of Publication:Cambridge, Englang
Language:eng
Publication Date:2016.

The Physical Object

Description:1 online resource (524 pages)

Edition Identifiers

ISBN:9781782624059, 1782624058, 9781782628194, 1782628193
oclc:ocn953234367
LC Classification:RA1224.3
Dewey Decimal:617

Introduction to Predictive Toxicogenomics for Carcinogenicity; Genomic Biomarkers in Cell-based Drug Screening; Toxicogenomics In Vitro: Gene Expression Signatures for Differentiating Genotoxic Mechanisms; In Vivo Signatures of Genotoxic and Non-Genotoxic Chemicals; Transcriptomic Dose-Response Analysis for Mode of Action and Risk Assessment; Using transcriptomics to evaluate thresholds in genotoxicity dose-response; Dissecting Modes of Action of Non-Genotoxic Carcinogens; Human Embryonic Stem Cells as Biological Models to Examine the Impact of Xenobiotics on the Genome and Epigenome; Novel Data Streams in the Assessment of Mutagenicity and Carcinogenicity: Implications for Cancer Hazard Assessment; Conazoles and Cancer, a Review; Application of Transcriptomics in Exposed Human Populations: Benzene as an Example; Toxicogenomics Case Study: Furan; The Parallelogram Approach to Assess Human Relevance of Toxicogenomics Derived Toxicity Pathways in Human Health Risk Assessment; Bioinformatics of Genomics in the Assessment of Cancer.