Toxicological carcinogenesis

How do we know if a chemical is carcinogenic? How accurate and relevant to humans are the current assays? With the increasing influx of chemicals in our food and environment, these questions become more critical everyday. Written by an expert with more than fifty years experience in this field, Toxicological Carcinogenesis gives you a balanced and authoritative treatment of the issues. The book provides a summary of the present knowledge of chemicals that induce cancer. The author avoids the overuse of technical jargon and explains scientific concepts clearly and succinctly. He has included an appendix containing bibliographic references, making the text easier to read and keeping the information available as a reference. He covers: How carcinogens are detected in humans using epidemiology, bioassays, and alternative approaches Agents leading to human cancer such as exposure due to occupation, cigarette smoking, and diet and nutritionCarcinogenesis mechanismsThe use of legislation to control exposures to noxious agents. Toxicological Carcinogenesis fills a gap in the current literature by providing just enough background information to give a complete general overview of the subject. It explores the emerging debates that related to the potential chemical causes of cancer. In addition to the comprehensive coverage the book provides, it explains the potential problems caused by possible misinformation about chemical carcinogenesis.

Introduction: What Causes Cancer. METHODS OF ESTABLISHING THAT CHEMICALS CAUSE CANCER. Epidemiology or Studies in Humans. Standard Animal Bioassays. Other Methods for the Detection of Carcinogens: Are They Quicker and Cheaper? SOURCES OF HUMAN EXPOSURE TO CARCINOGENS. Exposures in the Workplace. Cigarette-Smoking: A Modern Plague. Diet and Nutrition. Pharmaceuticals. The General Environment. Relevance of Rodent Carcinogens to Humans. REDUCING THE RISK OF CANCER. Carcinogenesis Mechanisms. Carcinogen Risk Assessment. Legislation, Regulation, and Education. Envoi-Can any Cancers be Prevented? Appendix. Index.