Transcription Factors

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The present volume, authored by leading experts in the field, contains in-depth information regarding the role of transcription factors as key players in the execution of the genomic program of any given cell. Many of the chapters focus on the role of transcription factors in cellular transformation and cancer, other chapters highlight the contributions of transcription factors to inflammatory responses or xenobiotic responses. Moreover, the volume illustrates how a viral transcription factor i…

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Title Statements

Full title :Transcription Factors / edited by Manfred Gossen, Jörg Kaufmann, Steven J. Triezenberg.

Summary

Edition Statements

Publication Date:2004.

Publication Statements

Publisher(s):Springer Berlin Heidelberg
Place of Publication:Berlin, Heidelberg
Language:eng
Publication Date:2004.

The Physical Object

Description:1 online resource (x, 581 pages 77 illustrations, 5 illustrations in color.)

Edition Identifiers

ISBN:9783642189326, 3642189326, 3540210954, 9783540210955
DOI:10.1007/978-3-642-18932-6
oclc:ocn851704805
LC Classification:RM1-950
Dewey Decimal:615

1. An Introduction to Transcription Factors -- Mechanisms of Transcriptional Activation in Eukaryotes -- Multiple Mechanisms of Transcriptional Repression in Eukaryotes -- Genomic Approaches to the Study of Transcription Factors -- 2. Transcription Factors in Pathophysiology -- Biological Roles of the STAT Family in Cytokine Signaling -- Members of the T-Cell Factor Family of DNA-Binding Proteins and Their Roles in Tumorigenesis -- Transcription Factors in the Control of Tumor Development and Progression by TGF-? Signaling -- The p53 Transcription Factor as Ther apeutic Target in Cancer -- The Role of Ets Transcription Factors in Mediating Cellular Transformation -- Function of the E2F Transcription Factor Family During Normal and Pathological Growth -- c-Myc in Cellular Transformation and Cancer -- NF-?B: Critical Regulator of Inflammation and the Immune Response -- Hepatitis BVirus X Protein: Structure-Function Relationships and Role in Viral Pathogenesis -- Regulation of Xenobiot ic Detoxification by PXR, CAR, GR, VDR and SHP Receptors: Consequences in Physiology -- 3. Exogenous Control of Transcription Factor Activity -- Potential of Transcription Factor Decoy Oligonucleotides…

Subjects

biochemistry Biochimie bioengineering Biotechnologie Biotechnology Genetic transcription Médecine Medicine medicines (material) Toxicologie Toxicology Transcription Factors -- genetics Transcription Factors -- pharmacology Transcription génétique Transcription, Genetic