Tuberculosis

by Shinnick, T. M., (Thomas M.)

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Title Statements

Full title :Tuberculosis / edited by Thomas M. Shinnick.

Summary

This volume addresses two important aspects of tuberculosis. The first half reviews some of the biochemistry, genetics, and molecular biology of M. tuberculosis and its interactions with macrophages. The second half deals with the interactions of the tubercle bacillus with the host immune system in experimental animals and humans, which may lead to the development of protective immunity or may produce immunopathologic reactions and tissue destruction. The special feature of this book is the in-depth nature of the various aspects of the bacterium and the host immune response to it. The reader will derive a better understanding of the tubercle bacillus and tuberculosis, and of the intricate interactions of the pathogen and the host which can lead either to protective immunity or to disease.

Edition Statements

Publication Date:1996.

Publication Statements

Publisher(s):Springer Berlin Heidelberg
Place of Publication:Berlin, Heidelberg
Language:eng
Publication Date:1996.

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:9783642801662, 3642801668, 9783642801686, 3642801684
DOI:10.1007/978-3-642-80166-2
oclc:ocn864569889
LC Classification:QR180-189.5
Dewey Decimal:616.079

List of Contents -- Mycobacterium tuberculosis Cell Envelope -- The Molecular Genetics of Mycobacterium tuberculosis -- Mechanisms of Drug Resistance in Mycobacterium tuberculosis -- Entry of Mycobacterium tuberculosis into Mononuclear Phagocytes -- In Vitro Interaction of Mycobacterium tuberculosis and Macrophages: Activation of Anti-mycobacterial Activity of Macrophages and Mechanisms of Anti-mycobacterial Activity -- Virulence Determinants of Mycobacterium tuberculosis -- Pathogenesis of Experimental Tuberculosis in Animal Models -- Immune Responses in Animal Models -- Human Cellular Immune Responses to Mycobacterium tuberculosis -- Mechanisms of Anergy in Tuberculosis -- The Koch Phenomenon and the Immunopathology of Tuberculosis -- BCG Vaccination in the Control of Tuberculosis -- Functional T Cell Subsets in Mycobacterial and Listerial Infections: Lessons from Other Intracellular Pathogens.

Subjects

Allergy and Immunology Aufsatzsammlung Immunologie Immunology Immunreaktion Internal Medicine Médecine Médecine interne Medicine medicines (material) microbiologie microbiology Mikrobiologie Mycobacterium tuberculosis -- immunology Tuberculose TUBERCULOSIS Tuberculosis -- immunology Tuberculosis -- therapy Tuberkelbakterium Tuberkulose