Vertebrate motoneurons

Vertebrate motoneurons

by Falgairolle, Mélanie O'Donovan, Michael J

Type Book
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This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about…

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Title Statements

  • Full title :Vertebrate motoneurons / Michael J. O'Donovan, Mélanie Falgairolle, editors.

Summary

This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease. Chapters from several of the foremost figures in the field are included in this book and will emphasize how basic science is the engine driving the discovery of novel treatments for degenerative motoneuron diseases. Cutting edge developments in the use of pluripotent stem cells to correct motoneuron disease will be also be covered. This book would be useful to students of basic motoneuron physiology, locomotor behavior and motor control. This book would also be of interest to professional neuroscientists, neurologists, and neurosurgeons.

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Edition Statements

  • Publication Date:2022.

Publication Statements

  • Publisher(s):Springer
  • Place of Publication:Cham
  • Language:eng
  • Publication Date:2022.

Notes

Identification of Signaling Pathways in Fly Embryo Motoneurons

The Physical Object

  • Description:1 online resource (403 pages)

Edition Identifiers

  • ISBN:9783031071676, 3031071670
  • DOI:10.1007/978-3-031-07167-6
  • oclc:on1344159936
  • LC Classification:QP369.5
  • Dewey Decimal:573.8/536

Table of Contents

Intro -- Preface -- Contents -- Part I: Motoneuron Development -- Establishing the Molecular and Functional Diversity of Spinal Motoneurons -- 1 Introduction -- 2 Anatomical and Functional Diversity of Spinal Motoneurons -- 3 Specification of Spinal Motoneuron Class Identity -- 4 Early Patterning of Spinal Motoneurons Along the Rostrocaudal Axis -- 5 Developmental Mechanisms of Motoneuron Diversification -- Hox Genes and the Specification of LMC Neurons and Divisional Subtypes -- Intrinsic Programs of Motoneuron Pool Specification -- Target-Dependent Regulation of Motoneuron Pool Identities

Development of Phrenic Motor Column (PMC) Neurons -- Development and Diversity of Preganglionic Column (PGC) Neurons -- Specification Hypaxial (HMC) and Medial Motor Column (MMC) Neurons -- Establishing Motoneuron Functional Subtype Diversity -- 6 Evolution of Spinal Motoneuron Organization and Function -- Origins of Tetrapod Limb Motoneurons -- Hox Genes and the Evolution of Motoneuron Segmental Organization and Diversity -- Divergence of Axial Motoneuron Specification Programs in Fish -- 7 Assembly of Proprioceptive Sensory-Motor Circuits

Specification of Proprioceptor Sensory Neuron Class …

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