Viral molecular machines

by Rao, Venigalla B. Rossmann, M. G., (Michael G.)

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Title Statements

Full title :Viral molecular machines / Michael G. Rossmann, Venigalla B. Rao, editors.

Summary

A biological organism can be viewed as a collection of molecular machines well integrated to function as a self-replicating unit. One of the principal goals in biology is to be able to fully understand the mechanisms of an organism in atomic detail. Viruses offer the best opportunities to achieve this goal. Written by leaders in the respective fields, this book examines a variety of viral molecular machines, using the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, assembly of structural components, genome packaging and maturation into an infectious virion. The book conveys the state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics. Viral Molecular Machines is not only a "must-have" book for virologists but it will also be broadly useful for molecular biologists in academia and industry as well as an educational tool for teaching graduate and upper level undergraduate students.

Edition Statements

Publication Date:©2012.

Publication Statements

Publisher(s):Springer
Place of Publication:New York
Language:eng
Publication Date:©2012.

The Physical Object

Description:xiv, 687 pages : : illustrations (some color) ; : 27 cm.

Edition Identifiers

ISBN:9781461409793, 1461409799, 9781461409809, 1461409802
oclc:ocn733250004
LC Classification:QR389
Dewey Decimal:579.2

Viruses: sophisticated biological machines / M.G. Rossmann and V.B. Rao -- F(1)-ATPase: A prototypical rotary molecular motor / K. Kinosita, Jr. -- Principles of virus structural organization / B.V. Prasad and M.F. Schmid -- Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography / J. Chang [and others] -- Contractile tail machines of bacteriophages / P.G. Leiman and M.M. Shneider -- Long noncontractile tail machines of bacteriophages / A.R. Davidson [and others] -- Short noncontractile tail machines: adsorption and DNA delivery by podoviruses / S.R. Casjens and I.J. Molineux -- Infection of cells by alphaviruses / D.T. Brown and R. Hernandez -- Influenza virus entry / M. Luo -- Molecular mechanisms of HIV entry / C.B. Wilen, J.C. Tilton and R.W. Doms -- Bunyavirus: structure and replication / T.S. Guu, W. Zheng and Y.J. Tao -- Viral polymerases / K.H. Choi -- Chaperonin-mediated folding of viral proteins / Z.L. Hildenbrand and R.A. Bernal -- Building the machines: scaffolding protein functions during bacteriophage morphogenesis / P.E. Prevelige and B.A. Fane -- Bacteriophage HK97 capsid assembly and maturation / R.W. …

Subjects

Bio-informatique Computational Biology DNA Packaging Fulltext Internet resources molecular virology Virologie moléculaire Virus Integration -- physiology Virus Replication -- physiology Viruses -- genetics Viruses -- ultrastructure