Title Statements
- Full title :Vitamins and hormones. / series editor, Gerald Litwack, PhD, Toluca Lake, North Hollywood, California.
Summary
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on nociceptin opioid. Key features: Expertise of the contributorsCoverage of a vast array of subjectsIn.
Read More ↓Edition Statements
- Publication Date:2015.
- Edition:First edition
Publication Statements
- Publisher(s):Academic Press
- Place of Publication:Waltham, MA
- Language:eng
- Publication Date:2015.
The Physical Object
- Description:1 online resource.
Edition Identifiers
- ISBN:9780128025932, 012802593X, 0128024437, 9780128024430
- oclc:ocn903118327
- LC Classification:QP552.O65
- Dewey Decimal:572.65
Table of Contents
Front Cover; Nociceptin Opioid; Copyright; Contents; Contributors; Preface; Chapter 1: Helix-Constrained Nociceptin Peptides Are Potent Agonists and Antagonists of ORL-1 and Nociception; 1. Nociception in Brief; 1.1. Opioid receptor-like receptor-ORL-1; 1.2. Nociceptin; 1.3. Interrogating the activation and address domains of nociceptin(1-17); 2. Prospecting the Importance of the N-Terminal Tetrapeptide of Nociceptin(1-17); 3. Other Modifications to Nociceptin(1-17); 4. The Importance of Structure in Nociceptin Analogues; 4.1. Importance of helicity; 4.2. Other nociceptin derivatives
5. Recent Advances in ORL-1 Active Nociceptin Peptides6. The Development of New Helix-Constrained Nociceptin Analogues; 6.1. Design of helix-constrained nociceptin analogues; 6.2. Helical structure of nociceptin(1-17)-NH2 analogues in water; 6.3. Nuclear magnetic resonance spectra-derived structures; 7. Biological Properties of Helical Nociceptin Mimetics; 7.1. Cellular expression of ORL-1 and ERK phosphorylation; 7.2. Agonist and antagonist activity of nociceptin(1-17)-NH2 and analogues; 7.3. Effects of helical constraint on biological activity in Neuro-2a cells
7.4. Stability and cell toxicity of …
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