Few ethical issues create as much controversy as invasive experiments on animals. Some scientists claim they are essential for combating major human disease, or detecting human toxins. Others claim the contrary, backed by thousands of patients harmed by pharmaceuticals developed…
This comprehensive review of recent scientific evidence examines the contributions of animal experimentation to human healthcare and toxicity prediction, its necessity during life and health sciences education, its impacts on student attitudes toward animals, and the extent to w…
Few ethical issues create as much controversy as invasive experiments on animals. Some scientists claim they are essential for combating major human disease, or detecting human toxins. Others claim the contrary, backed by thousands of patients harmed by pharmaceuticals developed…
"Few ethical issues create as much controversy as invasive experiments on animals. Some scientists claim they are essential for combating major human diseases, or detecting human toxins. Others claim the contrary, backed by thousands of patients harmed by pharmaceuticals develop…
[Publisher-supplied data] Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such m…
Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects…
Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors. This book provides an overview of the design cons…
New high throughput techniques in neuroscience and psychiatry have enhanced the development of experimental, customizable animal models that are predictive of human neuropsychiatric pathology and give vital insights on the mechanisms and pathways involved. In Psychiatric Disorde…
Zebrafish Models in Neurobehavioral Research
by Kalueff, Allan V., Cachat, Jonathan M.
fromNeuromethods
Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral…
This volume covers new technologies and methodologies that have appeared for the study of mouse development. It looks at new techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals, generation of conditional/inducible muta…