The metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutri…
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This volume seeks to familiarize readers with a diverse range of technologies and approaches for probing neuron and circuit architecture, and, when possible, to attach detailed protocols to help guide readers toward practical application. From classical lipophilic dye and conjug…
Since its inception, patch-clamp has continued to be widely considered the gold standard method to record ion channel activity. Patch-Clamp Methods and Protocols, Second Edition, provides a comprehensive collection of new techniques for the development of automated, high-through…
Modern Electroencephalographic Assessment Techniques: Theory and Applications presents numerous signal processing and connectivity analysis methodologies addressing a wide variety of clinical applications including epilepsy, schizophrenia, Alzheimer's disease and even alcoholism…
Super-Resolution Microscopy Techniques in the Neurosciences serves as a comprehensive description of current super-resolution techniques, including the physical principles that allowed for their development, some of the most recent neurobiological applications, and selected info…
Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultur…
Axon Growth and Regeneration: Methods and Protocols brings together a diverse set of techniques for the study of the mechanisms underlying central nervous system axon growth, consequently providing a resource that will aid in the development of repair strategies. After an introd…
Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques, or combinations of techniques, applied to specific species in either healthy or abnormal …
The only book on the market to cover the psychophysics, anatomy, physiology, and clinical deficits of the developing visual system in an accessible format and length. The visual system is the most commonly studied aspect of the nervous system and is the primary model for the stu…
Transcranial Magnetic Stimulation seeks to enable new and existing practitioners to learn and follow established TMS protocols. The individual chapters in this detailed volume describe methods for single and multiple pulse TMS as well as methods for TMS coupled with associated t…
Laser Scanning Microscopy and Quantitative Image Analysis of Neuronal Tissue brings together contributions from research institutions around the world covering pioneering applications in laser scanning microscopy and quantitative image analysis and providing information about th…
Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to study them with traditional techniques. Fortunately…