Clinical pharmacokinetics and pharmacodynamics: concepts and applications

by Rowland, Malcolm

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Title Statements

Full title :Clinical pharmacokinetics and pharmacodynamics : concepts and applications.

Edition Statements

Publication Date:2009
Edition:Fourth edition

Publication Statements

Publisher(s):Lippincott William & Wilkins
Place of Publication:Place of publication not identified
Language:eng
Publication Date:2009

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:0781750091, 9780781750097
oclc:on1058621075
LC Classification:RM301.5.R68 2009
Dewey Decimal:615/.7

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.

Subjects

Analytical, Diagnostic and Therapeutic … Biochemical Phenomena Chemical Phenomena CHEMOTHERAPY Chimiothérapie drug therapy Health & Biological Sciences Kinetics Metabolism metabolism (biological concept) Métabolisme Pharmacocinétique Pharmacokinetics Pharmacological Phenomena Pharmacy, Therapeutics, & Pharmacology Phenomena and Processes Physiological Phenomena therapeutics Thérapeutique