This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
"Compounds isolated from nature have long been known to possess biological profiles and pharmaceutical potential far greater than anything made by man. However, they are notoriously cumbersome to isolate and challenging to synthesize, and the path of natural products to viable d…
"This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are…
"Covering topics from individual molecules to systemic diseases, from basic concepts to advanced technologies, Pharmacogenomics in Drug Discovery and Development, Second Edition provides a practical, state-of-the-art and integrative view of the application of pharmacogenomics in…
Pharmaceutical amorphous solid dispersions
Pharmaceutical amorphous solid dispersions
'Pharmacokinetics and Toxicokinetics' provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach.
Chapter 1. The influence of routes of administration on ADME -- chapter 2. Mechanisms of absorption and permeation of xenobiotics -- chapter 3. In Vivo distribution of xenobiotics -- chapter 4. Elimination rate, clearance, and the theoretical models -- chapter 5. Renal excretion…
