Congestive heart failure

Comprehensive, state-of-the-art reference on all basic and clinical aspects of heart failure. Coverage includes an entire section on pharmacologic therapy and a twenty-chapter section on clinical approaches to acute and chronic heart failure. This edition has new chapters on impact and treatment of comorbidities, prevention of sudden cardiac death, rationale for use of anticoagulants, ultrafiltration, use of mechanical devices, and gene and cell therapy. Readers will find up-to-date information on genetics, surgical therapies, ventricular synchronization, defibrillator therapy, mechanical approaches to atrial fibrillation, left ventricular assist devices, ventricular support and ventricular remodeling surgery, and myocardial regeneration/cell transplantation.

Epidemiology of heart failure -- Cellular and molecular abnormalities in failing cardiac myocytes -- Determinants of cardiac remodeling and progression to heart failure -- Cytoskeletal abnormalities in cardiocytes during heart failure -- Abnormalities in calcium cycling in heart failure -- Abnormalities in cardiac contraction: systolic dysfunction -- Heart failure with normal ejection fraction -- Cellular, molecular, and structural changes during cardiac remodeling -- Remodeling of the cardiac interstitium in heart failure -- The renin-angiotensin system -- Sympathetic nervous system in heart failure -- Other neurohormonal systems -- Cytokines as mediators of disease progression in the failing heart -- The peripheral circulation in heart failure -- The kidney in heart failure -- Risk factors for heart failure -- Heart failure secondary to coronary artery disease -- The cardiomyopathic and inflammatory diseases -- Congestive heart failure as a consequence of valvular heart disease -- Congestive heart failure secondary to congenital heart disease -- Right heart failure -- Heart failure in cardiac tamponade, constrictive pericarditis, and restrictive cardiomyopathy -- Clinical pharma…