Cyclic Nucleotide Signaling

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Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.

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Title Statements

Full title :Cyclic Nucleotide Signaling

Summary

Edition Statements

Publication Date:2015

Publication Statements

Publisher(s):CRC Press
Place of Publication:Hoboken
Language:eng
Publication Date:2015

Notes

IMD-Felder maschinell generiert

Chapter 13: Dissecting the Physiological Functions of PKA Using Genetically Modified MiceBack Cover.

The Physical Object

Description:Online-Ressource (282 Seiten)

Edition Identifiers

ISBN:9781482235562, 1482235560, 9781482235579, 1482235579
oclc:on1020499484
LC Classification:QP370
Dewey Decimal:612.8/2

Front Cover; Contents; Series Preface; Preface; Editor; Contributors; Chapter 1: Discovery of Small Molecule EPAC Specific Modulators by High-Throughput Screening; Chapter 2: Cyclic Nucleotide Analogs as Pharmacological Tools for Studying Signaling Pathways; Chapter 3: High-Throughput FRET Assays for Fast Time-Dependent Detection of Cyclic AMP in Pancreatic [beta] Cells; Chapter 4: Assessing Cyclic Nucleotide Recognition in Cells : Opportunities and Pitfalls for Selective Receptor Activation; Chapter 5: Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters.

Chapter 6: Structural Characterization of Epac by X-Ray CrystallographyChapter 7: Sensory Neuron cAMP Signaling in Chronic Pain; Chapter 8: Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains; Chapter 9: Identifying Complexes of Adenylyl Cyclase with A-Kinase Anchoring Proteins; Chapter 10: Assessing Cyclic Nucleotide Binding Domain Allostery and Dynamics by NMR Spectroscopy; Chapter 11: A Protocol for Expression and Purification of Cyclic Nucleotide-Free Protein in Escherichia coli; Chapter 12: Cyclic Nucleotide Analogues as Chemical Tools for Interaction Analysis.