Dynamic systems biology modeling and simulation

Dynamic systems biology modeling and simulation

by DiStefano, Joseph J.,, III

Type Book
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Title Statements

  • Full title :Dynamic systems biology modeling and simulation / Joseph DiStefano III.

Edition Statements

  • Publication Date:January 2015.
  • Edition:Revised version

Publication Statements

  • Publisher(s):Academic Press
  • Place of Publication:London, UK
  • Language:eng
  • Publication Date:January 2015.

The Physical Object

  • Description:xxiv, 861 pages : : illustrations (some color) ; : 29 cm

Edition Identifiers

  • ISBN:9780124104112, 0124104118
  • oclc:ocn905229941
  • LC Classification:QH324.2

Table of Contents

Biosystem modeling & simulation : nomenclature & philosophy -- Math models of systems : biomodeling 101 -- Computer simulation methods -- Structural biomodeling from theory & data : compartmentalizations -- Structural biomodeling from theory & data : sizing, distinguishing & simplifying multicompartmental models -- Nonlinear mass action & biochemical kinetic interaction modeling -- Cellular systems biology modeling : deterministic & stochastic -- Physiologically based, whole-organism kinetics & noncompartmental modeling -- Biosystem stability & oscillations -- Structural identifiability -- Parameter sensitivity methods -- Parameter estimation & numerical identifiability -- Parameter estimation methods II : facilitating, simplifying & working with data -- Biocontrol system modeling, simulation, & analysis -- Data-driven modeling & alternative hypothesis testing -- Experiment design & optimization -- Model reduction & network inference in dynamic systems biology -- Appendix A. A short course in laplace transform representations & ODE solutions -- Appendix B. Linear algebra for biosystem modeling -- Appendix C. Input-output & state variable biosystem modeling : going deeper -- Append…

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