Dynamic systems biology modeling and simulation

Dynamic systems biology modeling and simulation

by DiStefano, Joseph J.,, III

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Title Statements

  • Full title :Dynamic systems biology modeling and simulation / Joseph DiStefano III.

Edition Statements

  • Publication Date:©2014

Publication Statements

  • Publisher(s):Academic Press
  • Place of Publication:London, UK
  • Language:eng
  • Publication Date:©2014

Notes

Issued in print: 2014.

The Physical Object

  • Description:1 online resource : : illustrations

Edition Identifiers

  • ISBN:9780124104938, 0124104932
  • oclc:ocn932054811
  • Dewey Decimal:570.113

Table of Contents

Computation & Scale in Biology; ; Overview of the Modeling Process & Biomodeling Goals; ; Looking Ahead: A Top-Down Model of the Chapters; ; References; ; 2 Math Models of Systems: Biomodeling 101; ; Some Basics & a Little Philosophy; ; Algebraic or Differential Equation Models; ; Differential & Difference Equation Models; ; Different Kinds of Differential & Difference Equation Models; ; Linear & Nonlinear Mathematical Models; ; Piecewise-Linearized Models: Mild/Soft Nonlinearities; ; Solution of Ordinary Differential (ODE) & Difference Equation (DE) Models; ; Special Input Forcing Functions (Signals) & Their Model Responses: Steps & Impulses; ; State Variable Models of Continuous-Time Systems; ; Linear Time-Invariant (TI) Discrete-Time Difference Equations (DEs) & Their Solution; ; Linearity & Superposition.

Laplace Transform Solution of ODEs; ; Transfer Functions of Linear TI ODE Models; ; More on System Stability; ; Looking Ahead; ; Exercises; ; References; ; 3 Computer Simulation Methods; ; Overview; ; Initial-Value Problems; ; Graphical Programming of ODEs; ; Time-Delay Simulations; ; Multiscale Simulation and Time-Delays; ; Normalization of ODEs: Magnitude- & Time-Scaling; …

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