Functional polymers for nanomedicine
Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymer…
Read More ↓Title Statements
- Full title :Functional polymers for nanomedicine / edited by Youqing Shen.
Summary
Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.
Read More ↓Edition Statements
- Publication Date:2013.
Publication Statements
- Publisher(s):Royal Society of Chemistry
- Place of Publication:Cambridge
- Language:eng
- Publication Date:2013.
The Physical Object
- Description:1 online resource (xii, 318 pages) : : chiefly color illustrations
Edition Identifiers
- ISBN:1849736200, 9781849736206, 9781849737388, 184973738X
- oclc:ocn847481668
- LC Classification:R857.N34
- Dewey Decimal:620.5
Table of Contents
Machine generated contents note: ch. 1 Targeted Drug Delivery in Oncology: Current Paradigm and Challenges / You Han Bae -- 1.1. Targeted Drug Delivery -- 1.1.1. Origins of Targeted Drug Delivery -- 1.1.2. Progress in Targeted Drug Delivery -- 1.2. Current Paradigm -- 1.3. Challenges to Current Paradigm -- 1.3.1. Challenges Present in the Carrier -- 1.3.2. Challenges Present in the Target -- 1.4. Revolution -- References -- ch. 2 Targeted Nanomedicines: Challenges and Opportunities / Jinming Gao -- 2.1. Introduction -- 2.2. Passive Targeting by Stealth Nanomedicines -- 2.2.1. Nanomedicine Clearance by the Reticuloendothelial System -- 2.2.2. Tumor Penetration by Nanomedicines -- 2.3. Active Targeting by Surface-Functionalized Nanomedicines -- 2.3.1. Cancer Specificity of Active Targeting Nanomedicines -- 2.3.2. Increased Clearance of Active Targeting Nanomedicines -- 2.3.3. Tumor Accumulation: Passive vs. Active Targeting Nanomedicines -- 2.4. Conclusion and Future Perspectives.
Contents note continued: Acknowledgements -- References -- ch. 3 Rational Design of Translational Nanocarriers / Youqing Shen -- 3.1. The Three Key Elements for Translational Nanomedicine -- 3.2. The 2R2S…
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