Gene therapy

Gene therapy

by Cooper, David N., (David Neil) Lemoine, Nicholas R.

Type Book
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Gene Therapy describes the delivery systems now available to target a given tissue with specific gene or oligonucleotide sequences, and explores the utility of animal modules as test systems. In the context of selected disease states, it summarises in vitro and in vivo studies and clinical trials performed to date.

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Title Statements

  • Full title :Gene therapy / edited by Nicholas R. Lemoine, David N. Cooper.

Summary

Gene Therapy describes the delivery systems now available to target a given tissue with specific gene or oligonucleotide sequences, and explores the utility of animal modules as test systems. In the context of selected disease states, it summarises in vitro and in vivo studies and clinical trials performed to date.

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Edition Statements

  • Publication Date:2006.

Publication Statements

  • Publisher(s):Taylor & Francis
  • Place of Publication:Abingdon, Oxon
  • Language:eng
  • Publication Date:2006.

Notes

Originally published: Oxford, UK: Bios Scientific Publishers, 1996.

The Physical Object

  • Description:1 online resource (360 pages)

Edition Identifiers

  • ISBN:9781003076919, 1003076912, 9781000102376, 1000102378, 9781000144680, 1000144682, 9781000119541, 1000119548
  • DOI:10.1201/9781003076919
  • oclc:on1197637468
  • LC Classification:RB155.8
  • Dewey Decimal:615.895

Table of Contents

Foreword: Gene therapy -- the hype, the reality and the future / R. Williamson -- 1. Scope and limitations of gene therapy / K. Sikora -- 2. Tissue-directed gene delivery systems / C.R. Middaugh, M. Chastain and C.T. Caskey -- 3. Retroviral vectors / W.H. Gunzburg and B. Salmons -- 4. Adenovirus vectors / C.J.A. Ring -- 5. Adeno-associated virus vectors for human gene therapy / J.S. Bartlett and R.J. Samulski -- 6. Liposome delivery systems / R.K. Scheule and S.H. Cheng -- 7. Development of mammalian artificial chromosome vectors: prospects for somatic gene transfer / Z. Larin -- 8. Infectious herpes vectors for gene therapy / J.-M.H. Vos, E.-M. Westphal and S. Banerjee -- 9. Role of animal models in gene therapy / J.R. Dorin and D.J. Porteous -- 10. Gene targeting as an approach to gene therapy / A. Porter -- 11. Cystic fibrosis / N.J. Caplen and E.W.F.W. Alton -- 12. Gene therapy for haemophilia B. / K. Kurachi and J.-M. Wang.

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