GTPases regulating membrane dynamics

by Balch, William Edward Der, Channing J. Hall, A., (Alan)

Type Book

Rate 0.0 /5

Details

Files

Reviews

Download

Title Statements

Full title :GTPases regulating membrane dynamics / edited by William E. Balch, Channing J. Der, Alan Hall.

Summary

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease. *Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission *Identification and characterization of GTPase GEFs, GAPs and effectors *General methodologies to study GTPase function in vitro and in vivo.

Edition Statements

Publication Date:©2005.

Publication Statements

Publisher(s):Elsevier Academic Press
Place of Publication:San Diego, California
Language:eng
Publication Date:©2005.

The Physical Object

Description:1 online resource (xliii, 692 pages, 6 unnumbered pages of plates) : : illustrations (some color).

Edition Identifiers

ISBN:0121828093, 9780121828097
oclc:ocm63109042
LC Classification:QP601
Dewey Decimal:572.696

Subjects

Animal Biochemistry Biologie Biomembran Cell Membrane -- physiology Cell membranes celmembranen Dynamik Eiwitten en enzymen enzyme Enzymes fosfoglyceraat kinase (gtp) Fusion membranaire GTP Phosphohydrolases -- physiology Guanosintriphosphatasen Health & Biological Sciences Human Anatomy & Physiology Membrane Fusion membranes Membranes (Biologie) Membranes (Biology)