Regulators and effectors of small GTPases
Methods in enzymology
by Hall, Alan, Simon, Melvin I., Der, Channing J., Balch, William E., Abelson, John
GTPases regulating membrane dynamics
by Hall, Alan, Der, Channing J., Balch, William E.
GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for …
GTPases regulating membrane dynamics
by Hall, Alan, Balch, William Edward, Der, Channing J.
GTPases regulating membrane dynamics
GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for …
Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular …
Ebolavirus and Marburgvirus (MARV) belong to the highly pathogenic Filoviridae family of viruses that cause severe hemorrhagic fever. I have employed two general strategies to study the envelope glycoprotein (GP) of Ebolavirus, MARV, and a novel virus, the California Academy of …