High-throughput metabolomics

High-throughput metabolomics: methods and protocols

by D'Alessandro, Angelo

Type Book
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This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data spar…

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Title Statements

  • Full title :High-throughput metabolomics : methods and protocols / edited by Angelo D'Alessandro, ...

Summary

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

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Edition Statements

  • Publication Date:©2019

Publication Statements

  • Publisher(s):Humana Press
  • Place of Publication:New York
  • Language:eng
  • Publication Date:©2019

Notes

Publié aussi sous forme numérique avec l'e-ISBN 978-1-4939-9236-2.

The Physical Object

  • Description:1 v. (XV-459 p.) : : illustrations en noir et en coul. ; : 26 cm

Edition Identifiers

  • ISBN:9781493992355, 149399235X
  • oclc:on1107669254
  • LC Classification:QP171
  • Dewey Decimal:572/.4

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