High throughput screening: methods and protocols

by Janzen, William P.

Type Book

Rate 0.0 /5

Details

Files

Reviews

Download

Title Statements

Full title :High throughput screening : methods and protocols / edited by William P. Janzen ...

Summary

"This third edition volume expands on the previous editions both by presenting more detailed protocols for the techniques described in the first and second editions of High Throughput Screening: Methods and Protocols and by covering important new procedures. The first chapter of this book provides an overview of important assay development techniques, while the rest of the chapters detail how to develop and execute screens at whatever throughput the user needs. Some chapter examples are: structure-based virtual screening, high throughput screening using mass spectrometry, identification of state-dependent blockers for voltage gated calcium channels, bioluminescence resonance energy transfer platform to monitor protein-protein interactions in live cells, high throughput flow cytometry, and application of imaging-based assays in microplate formats for high content screening. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, High Throughput Screening: Methods and Protocols, Third Edition, is a valuable resource for anyone who is interested in HTS research."--Page 4 de la couverture

Edition Statements

Publication Date:©2016.
Edition:Third edition

Publication Statements

Publisher(s):Humana Press
Place of Publication:New York
Language:eng
Publication Date:©2016.

The Physical Object

Description:1 v. (xi-308 p.) : : illustrations en noir et en coul. ; : 26 cm

Edition Identifiers

ISBN:9781493936717, 1493936719
oclc:ocn959832895
LC Classification:RS419.5

Subjects

Chemistry, Pharmaceutical Chimie pharmaceutique Chimie pharmaceutique -- Méthodes Combinatorial Chemistry Techniques Criblage à haut débit (Développement de… Criblage pharmacologique Drug Evaluation, Preclinical -- methods Évaluation préclinique de médicament --… High throughput screening (Drug develop… High throughput screening (Drug develop… Laboratory manuals Pharmaceutical chemistry Techniques de chimie combinatoire Tests de criblage à haut débit