High throughput screening methods: evolution and refinement

by Bittker, Joshua A. Ross, Nathan T.

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Title Statements

Full title :High throughput screening methods : evolution and refinement / editors: Joshua A. Bittker, Nathan T. Ross.

Edition Statements

Publication Date:2016.

Publication Statements

Publisher(s):Royal Society of Chemistry
Place of Publication:Cambridge, England
Language:eng
Publication Date:2016.

Notes

Includes index.

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:9781782626770, 1782626778
oclc:ocn966205630
LC Classification:RS419.5
Dewey Decimal:615.1/9

Perspective/overview: State of the art in HTS at the academic-industry interface; Assay design and optimization; Assessment of available compound collections; Novel approaches to discovery and analysis of interesting compound combinations; Modern biophysical methods in target-based screening; Genetic perturbation methods; Understanding luminescence-based screens; Measuring interactions in live cells; Approaches to high-content imaging and multi-feature analysis; Profiling of genetically characterized cell systems; Multidimensional profile-based screening; Using biological systems that better recapitulate physiology; Phenotypic screens with model organisms; Encoded libraries; Modern virtual screening; Research data management; Small molecule bioactivity databases; Chemical biology in a pharma environment; Practical aspects of funding and executing high-throughput screens

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