Human drug metabolism

Human drug metabolism

by Coleman, Michael D.

Type Book
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"The third edition of this key text continues to provide an invaluable introduction to the core areas of pharmacology, and covers recent progress and advances in this fast moving field. It will continue to cover basic concepts of teaching drug metabolism starting from extreme clinical consequences to systems and mechanisms and toxicity. The new edition will retain this basic layout, but will be fully updated to reflect advances in the scientific field of drug metabolism and its clinical impact.…

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Title Statements

  • Full title :Human drug metabolism / Michael D. Coleman.

Summary

"The third edition of this key text continues to provide an invaluable introduction to the core areas of pharmacology, and covers recent progress and advances in this fast moving field. It will continue to cover basic concepts of teaching drug metabolism starting from extreme clinical consequences to systems and mechanisms and toxicity. The new edition will retain this basic layout, but will be fully updated to reflect advances in the scientific field of drug metabolism and its clinical impact. It will also reflect refinements in the author's own teaching methods, particularly with respect to helping students to understand biological systems and how they operate so they can be seen as predictable, rather than the usual default rote-learning approach that many adopt. This approach has usually been confined to life-science students who might gravitate to research. However, the author is hoping to also help clinically active individuals, by enabling them to grasp a more sophisticated approach to drug metabolism and retain it to augment their professional performance"--

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Edition Statements

  • Publication Date:2020.
  • Edition:Third edition

Publication Statements

  • Publisher(s):Wiley-Blackwell
  • Place of Publication:Hoboken, NJ
  • Language:eng
  • Publication Date:2020.

The Physical Object

  • Description:xvii, 662 pages : : illustrations ; : 23 cm

Edition Identifiers

  • ISBN:9781119458562, 1119458560
  • oclc:on1112130481
  • LC Classification:RM301.55
  • Dewey Decimal:615.1

Table of Contents

Drug biotransformational systems: origins and aims -- How oxidative systems metabolize substrates -- Introduction of cytochrome P450 systems -- Cytochrome P450 inhibition -- Conjugation and transport processes -- Factors affecting drug metabolism -- Role of metabolism in drug toxicity.

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