Human Embryonic Stem Cells in Development

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Human Embryonic Stem Cells in Development, Volume 129, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as recapitulating pancreas development from human embryonic stem cells in a dish, modeling mammalian gastrulation with embryonic stem cells, and a section on what stem cells tell us about human germ cell biology. Each chapter is written by an international board o…

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Title Statements

Full title :Human Embryonic Stem Cells in Development / Ali H. Brivanlou, Ph. D.

Summary

Edition Statements

Publication Date:2018.
Edition:First edition

Publication Statements

Publisher(s):Academic Press, an imprint of Elsevier
Place of Publication:Cambridge, MA
Language:eng
Publication Date:2018.

The Physical Object

Description:1 online resource : : colour illustrations

Edition Identifiers

ISBN:9780128043349, 0128043342
oclc:on1037272346
LC Classification:QH588.S83
Dewey Decimal:616.02774

Front Cover; Human Embryonic Stem Cells in Development; Copyright; Contents; Contributors; Preface; Chapter One: Modeling Mammalian Gastrulation With Embryonic Stem Cells; 1. Introduction; 2. Mathematical Preliminaries; 3. Colony Architecture; 3.1. Growth in Two-Dimensional Micropatterns; 3.2. Three-Dimensional Culture Systems; 4. Spatial Patterning of Cell Fates; 4.1. Micropatterned Two-Dimensional Culture Systems; 4.2. Three-Dimensional Culture Systems; 5. Conclusions; Acknowledgment; References; Chapter Two: What Can Stem Cell Models Tell Us About Human Germ Cell Biology?; 1. Introduction

2. Signaling for Germ Cell Specification in Mammalian Embryos3. Permissive Cell State for Germ Cell Specification in the Embryo; 4. Inducing Germline Competency in Pluripotent Stem Cells; 5. Transcription Factors for Human Germ Cell Specification and Epigenetic Resetting; 6. In Vitro Germ Cell Induction Beyond PGC Specification; 7. Misregulation of Germ Cell Development; 7.1. Germ Cell Tumors; 7.2. Inheritance of Epigenetic Mutations Through the Germline; 7.3. Inheritance of Mitochondria Through the Female Germline; 8. Perspective; Acknowledgments; References; Further Reading

Chapter Three: …

Subjects

Cellules souches embryonnaires Embryo Research Embryonic stem cells HEALTH & FITNESS -- Diseases Human Embryonic Stem Cells MEDICAL -- Clinical Medicine MEDICAL -- Diseases MEDICAL -- Evidence-Based Medicine MEDICAL -- Internal Medicine