Metallomics: analytical techniques and speciation methods

Latest developments, new insights and knowledge derived from speciation analysis in one unique compilation: The reader gets acquainted with relevant instrumental as well as application aspects of metallomics approaches, paving the road to understanding fate, pathway, and action of metals in environment and organisms. Upon an introductory chapter on analytical methods and strategies, the full bandwidth of applications is discussed. Expert chapter authors cast spotlights on recent topics such as metallomics applications to environmental and nutrition studies as well as biology and medicine. Special chapters deal with the impact of manganese and iron on neurodegeneration, and the impact of nanoparticles on health.

Analytical Methods and Strategies in Metallomics. The Position of Metallomics Within Other Omics Fields / Dirk Schaumlaffel -- Coupling Techniques and Orthogonal Combination of Mass Spectrometric Techniques / Daniel Prufrock -- Quality Control in Speciation Analysis Using HPLC with ICP-MS and ESI MS/MS: Focus on Quantitation Strategies Using Isotope Dilution Analysis / Heidi G Infante -- Novel Methods for Bioimaging Including LA-ICP-MS, NanoSIMS, TEM/X-EDS, and SXRF / Dirk Schaumlaffel, Robert Hutchinson, Julien Malherbe, Philippe Le Coustumer, Etienne Gontier, Marie-Pierre Isaure -- Electrochemistry Coupled to Mass Spectrometry for Investigating Oxidative Metabolism of Pt-Based Drug Conjugates: A Novel Approach / Gunther Weber -- Metallomics in Environment and Nutrition. Selenium and Selenium Species / Maria Ochsenkuhn-Petropoulou, Fotios Tsopelas, Lena Ruzik, Katarzyna Bierla, Joanna Szpunar -- Arsenic and As Species / Maria Carmen Barciela-Alonso, Pilar Bermejo-Barrera, Jorg Feldmann, Andrea Raab, Helle R Hansen, Katharina Bluemlein, Dirk Wallschlager, Michael Stiboller, Ronald A Glabonjat, Georg Raber, Kenneth B Jensen, Kevin A Francesconi -- Analytical Procedures for Speciati…