Modern reduction methods

Reductions are the counterpart of oxidations and are widely used in synthetic organic chemistry. They vary widely in their specifics, ranging from hydrogenations to hydride transfer or simply electron transfers, and their vast number makes a comprehensive review virtually impossible. This monograph thus covers recent developments, focusing on general and synthetically useful reductions in frequent use by chemists. The high quality contributions treat the reduction of carbonyls, alkenes, imines and alkynes, as well as reductive aminations and cross and Heck couplings, as well as addressing areas such as kinetic resolutions and hydrogenolysis. With its comprehensive overview of modern reduction methods, this book allows readers to find reliable solutions quickly and easily, making it an indispensable lab companion for every organic, catalytic and natural products chemist, as well as chemists in industry.

Reduction of functionalized alkenes -- Hydrogenation of unfunctionalized alkenes -- The development and application of rhodium-catalyzed hydroboration of alkenes -- Alkene reduction : Hydrosilylation -- Carbonyl hydrogenation -- Reduction of carbonyl compounds by hydrogen transfer -- Carbonyl hydroboration -- Diverse modes of silane activation for the hydrosilylation of carbonyl compounds -- Enzyme-catalyzed reduction of carbonyl compounds -- Imine hydrogenation -- Imino reductions by transfer hydrogenation -- Hydroboration and diboration of imines -- Hydrosilylation -- Alkene and imino reductions by organocatalysis -- Alkyne reductions -- Metal-catalyzed reductive aldol coupling -- Dissolving metals -- Hydrometallations of unsaturated compounds.