Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development
by Eberhard, David A. Potts, Steven J. Wharton, Jr. Keith A.
Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepa…
Read More ↓Title Statements
- Full title :Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development / edited by Steven J. Potts, David A. Eberhard, Keith A. Wharton, Jr.
Summary
Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepatitis, arthritis, celiac disease, myeloproliferative disorders, neurology, and wound healing. The authors write from years of experience in diagnostic practice and pharmaceutical drug development, aiming to educate pharmaceutical and academic scientists how to best use tissue to diagnose disease and improve the process of drug development. As part of the Methods in Pharmacology and Toxicology series, this volume is designed to provide wisdom and examples that others can follow and apply as part of drug development. Comprehensive and practical, Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development will inform and enlighten both tissue-focused and non-tissue-focused drug development professionals about better use and interpretation of the multidimensional data contained in a tissue biopsy.
Read More ↓Edition Statements
- Publication Date:2015.
Publication Statements
- Publisher(s):Humana Press, Imprint, Springer New York
- Place of Publication:New York, NY
- Language:eng
- Publication Date:2015.
The Physical Object
- Description:1 online resource (XVIII, 375 pages 57 illustrations, 37 illustrations in color.) : : online resource.
Edition Identifiers
- ISBN:9781493926817, 1493926810, 9781493926800, 1493926802
- DOI:10.1007/978-1-4939-2681-7
- oclc:on1058312102
- LC Classification:RM1-950
- Dewey Decimal:615
Table of Contents
Histopathology: A Canvas and Landscape of Disease in Drug and Diagnostic Development -- A Field Guide to Homo morphologicus for Biomedical Scientists, Or How to Convey an Understanding of Pathology to Scientists in a Biopharma Enterprise -- Outsourcing Tissue Histopathology Investigations in Support of Clinical Trials for Novel Therapeutics: Considerations and Perspectives -- Histopathology in Mouse Models of Rheumatoid Arthritis -- Markers Used for Visualization and Quantification of Blood Vessels and Lymphatic Vessels -- Practical Approaches to Microvessel Analysis: Hotspots, Microvessel Density, and Vessel Proximity -- Quantitative Histopathology and Alternative Approaches to Assessment of Fibrosis for Drug Development in Hepatitis C and Nonalcoholic Steatohepatitis -- Stereology and Computer-Based Image Analysis Quantifies Heterogeneity and Improves Reproducibility for Grading Reticulin in Myeloproliferative Neoplasms -- Image Analysis Tools for Quantification of Spinal Motor Neuron Subtype Identities -- Development of a Tissue Image Analysis Algorithm for Celiac Drug Development -- Quantitative Histopathology for Evaluation of In Vivo Biocompatibility Associated with Biomedic…
Read More ↓Subjects
Writers
More from this Series
No reviews yet. Be the first to rate this work.
Related Works
more →
Pharmacology for anaesthesiologists
Microarray methods for drug discovery
Antiplatelet agents
Anticancer drug development
Activity-based protein profiling
Neurodegenerative Diseases
Files & Downloads
-
Molecular Histopathology and Tissue Biomarkers in…
PDF · 8.8 MB · updated -
Molecular Histopathology and Tissue Biomarkers in…
PDF · 9.4 MB · updated -
Molecular Histopathology and Tissue Biomarkers in…
PDF · 9.4 MB · updated
Rate & Review