Myogenesis in development and disease

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Myogenesis in Development and Disease, Volume 126, the latest volume in the Current Topics in Developmental Biology series, covers major topics of research in myogenesis, with a particular emphasis on regeneration and muscle disease. It includes contributions from an international board of authors, providing a comprehensive set of reviews.

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Title Statements

Full title :Myogenesis in development and disease / edited by David Sassoon.

Summary

Edition Statements

Publication Date:2018.

Publication Statements

Publisher(s):Academic Press, an imprint of Elsevier
Place of Publication:Cambridge, MA
Language:eng
Publication Date:2018.

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:9780128094945, 012809494X
oclc:on1017986343
LC Classification:QL951
Dewey Decimal:591.32

Front Cover; Myogenesis in Development and Disease; Copyright; Contents; Contributors; Preface; Chapter One: "What Did Maxwell's Equations Really Have to Do With Edison's Invention?": Addressing the Complexity; 1. Introduction; 2. The Innovation System Pipeline Leading to Clinical Intervention Creation; 3. The Relevance of Health Economics and Population Health in Decision-Making and the Complexity of a Degenerating Muscle; 4. The Price of Failure; 5. Concluding Comments; References; Further Reading; Chapter Two: The Muscle Stem Cell Niche in Health and Disease; 1. Introduction.

2. The Perinatal MuSC Niche3. The Quiescent MuSC Niche; 4. The Regenerative MuSC Niche; 4.1. The Inflammatory Niche; 4.2. The Mitogenic Niche; 4.3. The Differentiative Niche; 5. The MuSC Niche in Aging; 6. The Pathologic MuSC Niche; 7. Targeting the Niche for Therapy; 8. Concluding Remarks; References; Chapter Three: Translational Control of the Myogenic Program in Developing, Regenerating, and Diseased Skeletal Muscle; 1. Introduction; 1.1. Regulation of Translation; 1.2. Myogenesis; 1.2.1. Cell Fate Choices by Multipotent Progenitors.

1.2.2. Multiple Sequential Steps Define the Myogenic Program1.2.3. E…