Neurodegeneration: methods and protocols

by Kawamata, Hibiki Manfredi, Giovanni

Type Book

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Title Statements

Full title :Neurodegeneration : methods and protocols / edited by Giovanni Manfredi, Hibiki Kawamata.

Edition Statements

Publication Date:©2011.

Publication Statements

Publisher(s):Springer
Place of Publication:New York
Language:eng
Publication Date:©2011.

The Physical Object

Description:xv, 512 pages : : illustrations (some color) ; : 27 cm.

Edition Identifiers

oclc:ocn761893915
LC Classification:RC394.D35

Introduction to neurodegenerative diseases and related techniques -- In vivo and in vitro determination of cell death markers in neurons -- Degenerating processes identified by electron microscopic immunocytochemical methods -- Isolation and culture of neurons and astrocytes from the mouse brain cortex -- Isolation and culture of postnatal spinal motoneurons -- Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration -- Neural differentiation of induced pluripotent stem cells -- Developing yeast models of human neurodegenerative disorders -- Modeling dopamine neuron degeneration in Caenorhabditis elegans -- Role of the proteasome in fly models of neurodegeneration -- Modeling neurodegenerative diseases in zebrafish embryos -- Practical considerations of genetic rodent models for neurodegenerative diseases -- Modeling focal cerebral ischemia in vivo -- Pharmacological models of Parkinson's disease in rodents -- Behavioral phenotyping of mouse models of neurodegeneration -- Characterization of amyloid deposits in neurodegenerative diseases -- Detection of protein aggregation in neurodegenerative diseases -- Assessment of proteasome impairment a…