Oncogenomics: From Basic Research to Precision Medicine

by Silvestris, Franco

Type Book

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Title Statements

Full title :Oncogenomics: From Basic Research to Precision Medicine

Edition Statements

Publication Date:2019.

Publication Statements

Publisher(s):Academic Press
Language:eng
Publication Date:2019.

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:9780128117859, 0128117850, 9780128117866, 0128117869
oclc:on1229483518
LC Classification:RC268.4
Dewey Decimal:616.994042

Front Cover -- Oncogenomics -- Copyright Page -- Dedications -- Contents -- List of Contributors -- Preface -- I. Molecular medicine: a novel approach to cancer investigation -- 1 From the Double Helix to Oncogenomics and Precision Cancer Medicine: An Evolving Story -- Abbreviations -- The Double Helix and the Human Genome Project -- Precision Medicine Initiative and Precision Cancer Medicine -- Oncogenomics in the Fight Against Cancer -- Master Protocols and Clinical Trials of Targeted Drugs -- NSCLC and Melanoma: Successful Examples of Precision Cancer Medicine -- NSCLC -- Melanoma -- Precision Cancer Medicine: Uncertainties and Drawbacks -- Conclusions -- References -- 2 Intratumor Heterogeneity: Biological and Clinical Implications -- Introduction -- Levels of Intratumor Heterogeneity -- Genetic Heterogeneity -- Transcriptomic and Proteomic Heterogeneity -- Spatial Heterogeneity -- Phenotypic Heterogeneity -- Clinical Implications of Intratumor Heterogeneity and Novel Approaches -- Conclusions -- Acknowledgments -- References -- 3 The Role of Proteomics in Cancer Research -- What Is a Proteome? -- Proteomics Approaches in Cancer Research -- The Role of Proteomics in Cancer Res…