Protein engineering for therapeutics

Protein engineering for therapeutics

by Verdine, Gregory L., (Gregory Lawrence) Wittrup, K. Dane

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Title Statements

  • Full title :Protein engineering for therapeutics / edited by K. Dane Wittrup, Gregory L. Verdine.

Edition Statements

  • Publication Date:2012.
  • Edition:1st ed

Publication Statements

  • Publisher(s):Academic
  • Place of Publication:San Diego, Calif
  • Language:eng
  • Publication Date:2012.

The Physical Object

  • Description:2 volumes : : illustrations, plates (some color) ; : 23 cm.

Edition Identifiers

  • ISBN:9780124160392, 9780123969620, 0124160395, 012396962X
  • oclc:ocn779440055
  • LC Classification:QP601
  • Dewey Decimal:615.3

Table of Contents

pt. A. Section 1. Antibodies. Simplified synthetic antibody libraries / Saravanan Rajan and Sachdev S. Sidhu ; Generation of dual-variable-domain immunoglobulin molecules for dual-specific targeting / Jijie Gu and Tariq Ghayur ; Discovery of internalizing antibodies to tumor antigens from phage libraries / Yu Zhou and James D. Marks ; Optimizing properties of antireceptor antibodies using kinetic computational models and experiments / Brian D. Harms [and others] -- Section 2. Protein conjugates. Cell-specific siRNA delivery by peptides and antibodies / Sang-Kyung Lee [and others] ; Conjugation of anticancer drugs through endogenous monoclonal antibody cysteine residues / Robert P. Lyon [and others] ; Building and characterizing antibody-targeted lipidic nanotherapeutics / Dmitri B. Kirpotin [and others] ; Cell-targeting fusion constructs containing recombinant gelonin / Mi-Ae Lyu [and others] ; Fusions of elastin-like polypeptides to pharmaceutical proteins / Wafa Hassouneh, Sarah R. MacEwan, and Ashutosh Chilkoti -- Section 3. Enzymes. Oral enzyme therapy for celiac sprue / Michael T. Bethune and Chaitan Khosla ; Rational design and evaluation of mammalian ribonuclease cytotoxins…

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Subjects

protein engineering Protein Engineering -- methods Protéines -- Emploi en thérapeutique Proteins -- pharmacokinetics Proteins -- therapeutic use Technologie des protéines

Writers

Verdine, Gregory L., (Gregory Lawrence) Wittrup, K. Dane

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