Rat Genomics

by Dwinell, Melinda R. Hayman, G. Thomas Shimoyama, Mary Smith, Jennifer R.

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Title Statements

Full title :Rat Genomics / edited by G. Thomas Hayman, Jennifer R. Smith, Melinda R. Dwinell, Mary Shimoyama.

Summary

"This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project. In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investigation or to leverage a new technology. In other cases, a detailed review of existing models or a description of available resources can help the researcher find, understand, and utilize the information, the data, and the tools that they need to support their research efforts. Written as part of the highly successful Methods in Molecular Biology series, this collection includes the kind of hands-on detail necessary for success in the lab. " -- Prové de l'editor.

Edition Statements

Publication Date:©2019

Publication Statements

Publisher(s):Humana
Place of Publication:New York
Language:eng
Publication Date:©2019

Notes

Conté: 1. The Rat: A Model Used in Biomedical Research Jennifer R. Smith, Elizabeth R. Bolton, and Melinda R. Dwinell 2. Rat Genome Assemblies, Annotation, and Variant Repository Monika Tutaj, Jennifer R. Smith, and Elizabeth R. Bolton 3. Rat Genome Databases, Repositories, and Tools Stanley J.F. Laulederkind, G. Thomas Hayman, Shur-Jen Wang, Matthew J. Hoffman, Jennifer R. Smith, Elizabeth R. Bolton, Jeff De Pons, Marek A. Tutaj, Monika Tutaj, Jyothi Thota, Melinda R. Dwinell, and Mary Shimoyama 4. Next Generation Transgenic Rat Model Production Wanda E. Filipiak, Elizabeth D. Hughes, Galina B. Gavrilina, Anna K. LaForest, Michael G. Zeidler, and Thomas L. Saunders 5. Embryonic Stem Cells and Gene Manipulation in Rat Masumi Hirabayashi, Akiko Takizawa, and Shinichi Hochi 6. Protocols for Cryopreservation and Rederivation of Rat Gametes Akiko Takizawa and Tomoo Eto 7. Fluorescent Imaging and Microscopy for Dynamic Processes in Rats Ruben M. Sandoval, Bruce A. Molitoris, and Oleg Palygin 8. Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter Yong Liu, Alison J. Kriegel, and Mingyu Liang 9. Characterization of the Rat Gut Microbiota via 16S rRNA Amplicon Library Sequencing Aaron C. Ericsson, Susheel B. Busi, and James M. Amos-Landgraf 10. Networking in Biology: The Hybrid Rat Diversity Panel Boris Tabakoff, Harry Smith, Lauren A. Vanderlinden, Paula L. Hoffman, and Laura M. Saba 11. Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits Leah C. Solberg Woods and Abraham A. Palmer 12. Mapping Mammary Tumor Traits in the Rat Michael J. Flister, Amit Joshi, Carmen Bergom, and Hallgeir Rui 13. Rat Models of Metabolic Syndrome Anne E. Kwitek 14. Genomic Research in Rat Models of Kidney Disease Yoram Yagil, Ronen Levi-Varadi, and Chana Yagil 15. Rat Models of Exercise for the Study of Complex Disease Lauren Gerard Koch and Steven L. Britton 16. Behavioral Genetic Studies in Rats Yangsu Ren and Abraham A. Palmer.