Skin barrier function
by Agner, Tove
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdis…
Read More ↓Title Statements
- Full title :Skin barrier function / volume editor, Tove Agner.
Summary
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.
Read More ↓Edition Statements
- Publication Date:2016.
Publication Statements
- Publisher(s):Karger
- Place of Publication:Basel
- Language:eng
- Publication Date:2016.
The Physical Object
- Description:1 online resource
Edition Identifiers
- ISBN:9783318055863, 3318055867
- oclc:ocn944327481
- LC Classification:QM481
- Dewey Decimal:612.7/9
Table of Contents
Filaggrin and skin barrier function -- Stratum Corneum lipids: their role for the skin barrier function in healthy subjects and atopic dermatitis patients -- Importance of tight junctions in relation to skin barrier function -- Antimicrobial peptides, infections and the skin barrier -- Biological variation in skin barrier function: from A (atopic dermatitis) to X (xerosis) -- Methods for the assessment of barrier function -- In vivo raman confocal spectroscopy in the investigation of the skin barrier -- Irritants and skin barrier function -- Skin barrier function and allergens -- Penetration through the skin barrier -- Treatments improving skin barrier function -- Standards for the protection of skin barrier function -- The role of the skin barrier in occupational skin diseases -- Wet work and barrier function -- Saving the barrier by prevention.
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