Systemic lupus erythematosus

Systemic lupus erythematosus: methods and protocols

by Eggleton, Paul,, Dr Ward, Frank J.,, Dr

Type Book
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Systemic Lupus Erythematosus: Methods and Protocols describes a number of genetic, biochemical and immunological techniques. These techniques provide an?advancing understanding of the pathology, breakdown of the immune system, and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily…

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Title Statements

  • Full title :Systemic lupus erythematosus : methods and protocols / edited by Paul Eggleton, Frank J. Ward.

Summary

Systemic Lupus Erythematosus: Methods and Protocols describes a number of genetic, biochemical and immunological techniques. These techniques provide an?advancing understanding of the pathology, breakdown of the immune system, and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.--

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Edition Statements

  • Publication Date:2014

Publication Statements

  • Publisher(s):Humana Press
  • Place of Publication:New York
  • Language:eng
  • Publication Date:2014

The Physical Object

  • Description:xvii, 263 pages : : illustrations ; : 27 cm

Edition Identifiers

  • ISBN:9781493903252, 149390325X
  • oclc:ocn870978479
  • LC Classification:RC924.5.L85
  • Dewey Decimal:616.772

Table of Contents

Pathology of Systemic Lupus Erythematosus -- The Challenges Ahead -- The Lupus Biomarker Odyssey: One Experience -- Detection of Anti Nuclear Antibodies in SLE -- Tests for Circulating Immune Complexes -- Methods for Measuring Antibody Dependent Cell-Mediated Cytotoxicity in vitro -- Recombinant Antibody Microarray for Profiling the Serum Proteome of SLE -- Bi-functional Antibody Fragment-based Fusion Proteins for the Targeted Elimination of Pathogenic T-cell Subsets -- TLC Immunostaining for Detection of?Anti-Phospholipid? Antibodies -- Induced Murine Models of Systemic Lupus Erythematosus -- Measuring Interferon Alpha and other Cytokines in SLE -- Detection of SLE antigens in Neutrophils Extracellular Traps (NETs) -- Detection and Characterization of Autoantibodies Against Modified Self-proteins in SLE Sera after Exposure to Reactive Oxygen and Nitrogen Species -- Generation of Self-peptides to Treat Systemic Lupus Erythematosus -- Measurement of Malondialdehyde, Glutathione and Glutathione Peroxidase in SLE Patients -- Evaluating a Particular Circulating MicroRNA Species from an SLE Patient using Stem Loop qRT-PCR -- Microarray Technology for Analysis of MicroRNA Expression in …

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