The orexin/hypocretin system

The orexin/hypocretin system

by Nishino, Seiji Sakurai, Takeshi

Type Book
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It has been found that orexin/hypocretin impairment results in narcolepsy and cataplexy in humans and animals, leading to the possibility of better means of diagnosis and treatment. In this collection of 27 papers, which includes contrasting findings and an overview of the research conducted so far, contributors describe their research in the orexin/hypocretin system, its function in tissues and biological fluids, its physiology and pathophysiology. Specific topics include orexin and its recept…

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Title Statements

  • Full title :The orexin/hypocretin system / edited by Seiji Nishino and Takeshi Sakurai.

Summary

It has been found that orexin/hypocretin impairment results in narcolepsy and cataplexy in humans and animals, leading to the possibility of better means of diagnosis and treatment. In this collection of 27 papers, which includes contrasting findings and an overview of the research conducted so far, contributors describe their research in the orexin/hypocretin system, its function in tissues and biological fluids, its physiology and pathophysiology. Specific topics include orexin and its receptors, neurontal responses to orexin/hypocretin, and afferent systems, hypocretin measurements in blood and tissues, the feeding behavior of the orexin system and its relation with the autonomic nervous system and the neuroendocrine system, stress and emotion, hypocretin as a wakefulness regulatory peptide and as a component in motor function. Papers on pathophysiology cover human and canine models of narcolepsy, rodent models of human narcolepsy-cataplexy, hypocretin in psychiatric disorders, narcolepsy and.

Immunity, and treatment by such means as replacement therapy and ectopic overexpression of orexin peptides. Annotation : 2005 Book News, Inc., Portland, OR (booknews.com).

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Edition Statements

  • Publication Date:©2006.

Publication Statements

  • Publisher(s):Humana Press
  • Place of Publication:Totowa, N.J
  • Language:eng
  • Publication Date:©2006.

The Physical Object

  • Description:xii, 397 pages : : illustrations (some color) ; : 26 cm

Edition Identifiers

  • ISBN:1588294447, 9781588294449
  • oclc:ocm62700581
  • LC Classification:QP572.O74
  • Dewey Decimal:612.4/05

Subjects

Narcolepsie Narcolepsy Orexines Orexins

Writers

Nishino, Seiji Sakurai, Takeshi

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