Feedback control in systems biology
by Cosentino, Carlo, Cosentino, Carlo, Bates, Declan
Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty' such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedba…
This book demonstrates how feedback control concepts can be applied to systems biology. Each chapter introduces a field within control engineering and provides several applications in cellular biology. Chapters focus on the essential ideas and concepts from control theory that h…
Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty' such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedba…
Introduction -- Linear systems -- Nonlinear systems -- Negative feedback systems -- Positive feedback systems -- Model validation using robustness analysis -- Reverse engineering biomolecular networks -- Stochastic effects in biological control systems.