Tetrahydrobiopterin (BH4) is an essential cofactor for neuronal nitric oxide synthase (nNOS), yet the question of whether neurons that secrete nitric oxide (NO) synthesize BH4 remains unanswered. Cerebellar granule cell cultures (CGC) offer a model system of NO-producing neurons…
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Yield and reliability are two factors affecting the profitability of semiconductor manufacturing. In the manufacturing process of modern VLSI semiconductor devices, gate-oxide defects have been found as one of the major causes for the reliability problems of CMOS integrated circ…