Patel, Hetal

Chronic Myeloid Leukaemia (CML) arises as a consequence of the expression of a chimaeric fusion protein; p210BCR-ABL. Many publications report that p210BRR-ABL forms complexes with multiple cytoplasmic proteins which affect signalling pathways demonstrated in cell lines or trans…

The thesis investigates the relationship between the biomechanical properties of the anterior human sclera and cornea in vivo using Schiotz tonometry (ST), rebound tonometry (RBT, iCare) and the Ocular Response Analyser (ORA, Reichert). Significant differences in properties were…