Reid, Anne Marie

This thesis seeks to develop an understanding of knowledge creation processes in partnership working, conditions which foster these, and their impact on longer-term sustainability. The partnership, between a university in Greater Manchester and the Strategic Health Authority, wa…

RKIP was initially discovered as an endogenous inhibitor of the ERK and NF-κB pathways,and was also shown to prolong the activation of GPCRs via inhibition of the GRK2 protein. Now increasing evidence has linked RKIP to a metastases suppressing and chemo-sensitising role in canc…