The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a ph…
Preface -- 1 General mechanisms of gene vaccines -- 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System -- 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis -- 4 Cytokine genes as m…
