תסמונת דחק בתר-טראומטית נגרמת בעקבות חשיפה לגורם דחק אקוטי, בלתי נשלט ובלתי צפוי שעלול לגרום לפגיעה פסיכולוגית ותפקודית משמעותית. עם, המנגנונים הנוירוביולוגיים שעומדים מאחורי התסמונת אינם ברורים. על מנת להאיר מנגנונים אלה, נעשה שימוש במודלים שונים של התסמונת בבעלי חיים כמו טראומ…
Correct diagnosis of disease is essential in the effort to save and improve lives. Point of care (POC) diagnostics are in-vitro tests that assist in patient diagnosis and can be used at the location of patient care. POC diagnostics are easy to use and provide near-instant readou…
The effect of different levels of virus neutralizing maternally derived antibodies (MA) on protection against Infectious Bursal Disease Virus (IBDV) was investigated. Broiler chicks originating from three breeder flocks were used. Chicks from the above flocks were challenged at …
The Early Growth Response genes 2 and 3 (Egr2/3) are zinc finger transcription factors that play an important role in the immune system. These transcription factors have reported functions in T cell receptor signaling, differentiation of effector T cell subsets and the developme…
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) emerged in 2002/2003, causing the deaths of almost a tenth of the 8000 individuals infected worldwide before it was controlled by public health measures. While the 2003 epidemic strain is likely extinct, the importance…
Multiple sclerosis (MS) is the most common cause of acquired neurological disability in young adults. It is a multifocal disease defined histologically by multiple inflammatory lesions of demyelination, axonal injury, astrogliosis and varying degrees of remyelination. MS has two…
Cell-free circulating DNA (cfDNA) released from dying cells is emerging as an important tool for the diagnosis of disease. However, the utility of cfDNA is limited in conditions in which involved tissues have a normal genome or unknown mutations. I have developed an approach to …