This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs, and outlines the most up to date evidence regarding the treatmen…
This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.
This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.
This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific evidence on the efficacy and safety of antidepressants…
This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific evidence on the efficacy and safety of antidepressants…
"Combining a scholar's care and thoroughness with searing personal insight, David A. Karp brings the private experience of depression into sharp relief, drawing on a remarkable series of intimate interviews with fifty depressed men and women. By turns poignant, disturbing, morda…
"Combining a scholar's care and thoroughness with searing personal insight, David A. Karp brings the private experience of depression into sharp relief, drawing on a remarkable series of intimate interviews with fifty depressed men and women. By turns poignant, disturbing, morda…
Speaking of Sadness, based on fifty in-depth interviews, provides first-hand accounts of the depression experience while discovering clear regularities in the ways that personal identities are shaped over the course of an ""illness career."" The book also emphasizes the inextric…
This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and lo…
Objective. To examine the prevalence of comorbid mental health disorders (MHD) and personality disorders (PD) in adults with attention-deficit hyperactivity disorder (ADHD) and specific learning disorders (SLD). Furthermore, to identify whether the nature of these comorbidities …
The kynurenine pathway of tryptophan degradation is the focus in a variety of research fieldsand several of the metabolites produced along the pathway are suggested as future biomarkers.Growing interest in a better understanding of the physiological and the pathophysiologicalimp…
Mental health professionals have difficulty distinguishing Borderline Personality Disorder (BPD) and Bipolar Disorder due to overlapping clinical and etiological features. Such difficulties may lead to misdiagnoses and inappropriate treatment recommendations; thus, it is crucial…
Theoretical and empirical work suggest that reactivity to stress and responsivity to reward are correlated domains of functioning, and that dysfunction in the stress and reward systems may underlie Major Depressive Disorder (MDD). The goals of the current study are to examine: (…
Anxiety has a long, extensive history dating back to the ancient Greek physician Hippocrates and his published works (de Lijster, 2019, p. 9). Anxiety today is one of the most widespread diagnoses in the United States. In 2018, 3.1% of the Unites States population, or 6.8 millio…
The aim of this dissertation is to determine whether depression is associated with clinical (relapses and disability worsening) and MRI outcomes in multiple sclerosis (MS) by conducting a secondary data analysis of the CombiRx clinical trial. Psychiatric comorbidities, including…
