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The 15 lectures in this book provide an introduction to the ‘bigger picture’, followed by practical discussion on how each of the components interacts with one another. This book has been rigorously updated for its fourth edition to reflect today’s immunology teaching and includ…
Antigen processing is a biological process that prepares antigens for the presentation to special cells in the immune system called T lymphocytes. In Antigen Processing: Methods and Protocols, expert researchers in the field provide a comprehensive set of protocols for studying …
Discusses the role of nutrients as important cofactors and regulators of immune response. Topics covered include expression of nutrient interaction in immune function; the effect of nutritional conditioning on immune response; nutrient modulation of immune response in human deve…
Display technologies have become a very powerful way of generating therapeutic lead molecules and specific reagents for increasing our understanding of biology; however, despite being first described shortly after phage display, the use of ribosome display and related methods ha…
Anticarbohydrate Antibodies -- from molecular basis to clinical application compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relev…
The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed more than 25 years ago. However, initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bisp…
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Most human pathogens utilize mucosal surfaces to access the host. This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the…
The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly product…
This third edition of How the Immune System Works provides an introduction to the essential principles of the immune system. New features of the third edition include: More material on cancer and the immune system; Expanded coverage of immune system regulation with a chapter "Tu…
