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This volume explores the mechanisms of resistance to targeted therapeutics.¡The focus is on the cancer cell signaling network, ¡although other mechanisms of resistance including target¡mutation, and new areas of study such as cancer stem cells are included.¡ Targeted Therapies: …
The last decade has seen a renaissance of the concept of individualized chemotherapy in oncology, markedly stimulated by the development of new in vitro chemosensitivity assays. The clinical utility of drug response assays has been evaluated in clinical trials and the results su…
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
"Anticancer Therapeutics provides a comprehensive overview of the wealth of information now available in this important and fast-moving subject. The book provides a clear introduction to the area, with an overview of the various drug design and development approaches for cancer …
