Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects…
The carcinogenic mechanism of hepatobiliary and pancreatic tumors is poorly understood, making the development of rational treatment strategies difficult. The Syrian hamster is a unique animal for studying these neoplasms. This title explains various methods for the successful i…
The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgeni…
Several compounds are associated with experimentally induced neoplasms in the urinary systems, and especially the kidneys, of laboratory animals. Many of these neoplasms are succintly described and illustrated in detail in this volume, and some are compared with spontaneously oc…