The barn swallow (Hirundo rustica) is represented by six subspecies and has two well-studied ornamental traits, tail length and ventral plumage colour, which vary geographically among subspecies. Sexual selection on these traits has been suggested to drive speciation. The Europe…
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Many neurodegenerative disorders are characterised by protein misfolding and subsequent amyloid fibrillisation and deposition. Amyloid-beta peptide (Aβ) was found to be the main constituent of the extracellular amyloid plaques of Alzheimer’s disease (AD) in the 1980s. What trigg…
The ability of Shigella flexineri to spread within and between epithelial cells is essential for Shigella infection causing bacillary dysentery. This is a particular problem in the developing world. The movement of Shigella within the host cell requires the accumulation of actin…
TetratricoPeptide Repeats or TPRs are a class of repeat proteins made up of - helices. Each repeat contains 34 amino acids that form a helix-turn-helix motif and is stabilised by short range interactions creating a non-globular fold. Tandem arrays of these repeats form stable su…
The field of nanomedicine has witnessed an incredible expansion, from a total market value in 2003 of 500 million expected to rise to 160 billion by 2015 (Global Industry Analysts, Inc.). The nanomedicine industry is forecasted to grow and have a significant impact on the econom…
The seasonal variation of anammox is yet to be comprehensively studied, unlike denitrification, the more traditional sink for fixed nitrogen. A seasonal study of anammox, denitrification and benthic oxygen consumption using the revised isotope pairing technique is presented in C…
Multi-substituted optically pure cyclopropanes are important motifs present in many agrochemicals, pharmaceuticals and materials employed in manifold applications. Their synthesis is challenging due to both the strained conformation and the need to control both the relative and …
Saltmarshes in SE England are eroding rapidly and one potential impact is the loss of habitat for fishes. Saltmarshes have been created by setting back the existing line of flood defence through managed realignment. The use by fishes of natural and managed realignment habitats a…
Habitat loss and fragmentation are global threats to biodiversity, however, their impact on ecological function are not well understood. The Atlantic Forest hosts high levels of biodiversity and has experienced a long history of deforestation and fragmentation. To examine the co…
Many freshwater ecosystems sustain several invasive species. Here I examine multiple invasions in two highly invaded and well catalogued catchments; Lake Naivasha, Kenya and River Thames, England. New metrics, derived from stable isotope analysis, are used to provide measures of…