BRCA

Women with a BRCA (BReast CAncer) gene mutation carry a significantly increased lifetime risk of breast, ovarian, and other cancers compared to the general population. The United States Preventative Services Task Force (USPSTF) has issued a Grade B recommendation that primary ca…

Black women are starting to be recognized as a high-risk group for breast cancer. In addition to Black women having a relatively high incidence rate and the highest mortality rate, Black breast cancer patients were found to have an alarming rate of the BRCA1/2 genetic mutation. …

In February 2019, the American Society of Breast Surgeons (ASBrS) released a guideline recommending genetic testing be made available to all women with a breast cancer diagnosis. This guideline was based on findings in several papers outlining the number of individuals harboring…

Although colorectal cancer (CRC) is the third most common cancer in the United States, 75% of CRC occurs in individuals with no known risk factors. In this dissertation, I explore the importance of ancestral heritage, family history of cancer, BRCA mutations, APC D1822V, APC I13…